Phencyclidine (PCP) Addiction: Signs, Causes, Effect, Withdrawal, Treatment and Prevention

Phencyclidine (PCP) addiction is a serious concern due to its powerful psychoactive effects and high potential for dependence. Originally developed as an anesthetic, PCP, also known as “Angel Dust,” alters perception and induces feelings of detachment from reality.

Its ability to distort mood, vision, and perception contributes to its addictive nature, leading to significant risks for regular users. In 2023, the National Survey on Drug Use and Health reported that 24,000 individuals aged 12 and older tried PCP for the first time, adding to the estimated 8.8 million people who used hallucinogens that year.

Categorized as both a hallucinogenic and dissociative drug, Phencyclidine (PCP) produces a dual impact on the brain, altering sensory perceptions and causing a sense of detachment from the self and the environment. This classification is due to its impact on the central nervous system (CNS), which leads to significant behavioral and psychological shifts that make individuals feel disconnected from their thoughts, emotions, and surroundings.

The symptoms of Phencyclidine (PCP) addiction include hallucinations, delusions, memory issues, and mood disturbances. Individuals under the influence of PCP display erratic behavior, aggression, and impaired motor skills, among other physical symptoms like dilated pupils and numbness. These indicators are necessary for identifying PCP abuse early, as prolonged use exacerbates these effects and increases the risk of severe health issues leading to coma and death.

The causes of Phencyclidine (PCP) addiction include genetic susceptibility, environmental factors, and psychological triggers such as stress or trauma that fuel PCP addiction. Social settings, access to drugs, and personal mental health all contribute to initial and continued PCP use, ultimately leading to dependency. 

The health effects of Phencyclidine (PCP) abuse are both immediate and long-lasting, ranging from short-term risks like nausea and muscle stiffness to serious long-term consequences, including brain damage, respiratory issues, and increased risk of psychosis. Regular use also increases the likelihood of seizures, heart complications, and, in extreme cases, death due to respiratory depression or seizures.

Withdrawal from Phencyclidine (PCP) is challenging, as the body and brain struggle to adapt to the absence of the drug. Common withdrawal symptoms include anxiety, depression, cravings, and cognitive difficulties, with severity varying depending on the length and intensity of prior PCP use. PCP withdrawal lasts for 7 to 14 days, with symptoms peaking in severity within the first few days after the last dose, according to Delamere titled “Drug Addiction Withdrawal & Symptoms.”

Treatment options for Phencyclidine (PCP) addiction include medically supervised detoxification, cognitive behavioral therapy, and counseling. Each approach aims to address the root causes of addiction and develop coping strategies.

Medication-assisted treatment (MAT) also helps manage withdrawal symptoms and prevent relapse, improving the effectiveness of recovery when combined with counseling and rehabilitation. Healthline notes that nearly 75% of people who begin cognitive behavioral therapy (CBT) experience positive results.

According to NIDA, 50% of patients who remain in rehab for at least three months stay clean for at least two years. 

Preventing Phencyclidine (PCP) addiction involves education, strong social support networks, and early intervention. By raising awareness about the risks of PCP, particularly among young people, and promoting healthier coping mechanisms, communities reduce the likelihood of individuals developing a dependency on Phencyclidine (PCP).

Distinguishing Phencyclidine (PCP) abuse from addiction is important, as abuse refers to occasional, harmful use that leads to addiction. Addiction, however, is characterized by a compulsive need for the drug despite adverse consequences. Both forms of misuse require intervention, but addiction requires more comprehensive, long-term treatment.

Compared to other substance addictions, Phencyclidine (PCP) addiction shares similar traits with other hallucinogens and stimulants like LSD and cocaine but is noted for its intense psychological effects and high risk of aggression and self-harm. Treatment strategies vary based on the unique impacts of PCP on the brain, making recovery an intricate, individualized process for those affected.

What is Phencyclidine (PCP) Addiction? 

Phencyclidine (PCP) addiction is a condition where individuals develop a strong dependency on the hallucinogenic drug PCP, characterized by a compulsion to seek and use the substance despite its harmful consequences repeatedly. PCP, originally designed as an anesthetic, affects the brain by blocking the NMDA receptors, which play a key role in pain perception, memory, and learning.

This disruption leads to dissociative effects, hallucinations, and altered perceptions of reality. Over time, repeated use of PCP causes the brain to become reliant on the substance, leading to addiction.

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PCP addiction is less common than other drug addictions, but it remains a significant concern. According to the National Institute on Drug Abuse (NIDA), approximately 1.1 million people in the U.S. aged 12 or older have reported using PCP at least once in their lifetime. Globally, while precise statistics are harder to come by, PCP use is particularly prevalent in certain areas, including parts of Asia, Europe, and the U.S. The drug’s addictive nature and its profound impact on mental health and cognitive function make it a challenging substance to manage in addiction recovery.

What Are the Signs of PCP Addiction? 

The signs of Phencyclidine (PCP) addiction include extreme changes in behavior, physical appearance, and mental health. Behaviorally, individuals display violent outbursts, aggression, or erratic actions.

Physical signs of addiction include lack of coordination, slurred speech, and an unkempt appearance. Chronic PCP users exhibit weight loss, poor hygiene, and neglect of personal care.

Mentally, addiction manifests as anxiety, depression, or mood swings, as well as a detachment from reality. 

The behavioral, physical, and mental signs of Phencyclidine (PCP) addiction are as follows:

Behavioral Signs

The behavioral signs of Phencyclidine (PCP) addiction include aggression, isolation, and erratic actions. Those struggling with addiction exhibit sudden and extreme changes in behavior, such as violent outbursts or engaging in risky, impulsive activities.

These individuals withdraw from social interactions, becoming increasingly isolated or paranoid. They might also display bizarre or unpredictable behavior as a result of the drug’s hallucinatory effects.

This behavioral volatility is concerning, especially as the addiction deepens, leading to deterioration in personal relationships and daily functioning.

The behavioral signs of Phencyclidine (PCP) addiction are as follows:

• Aggression or violent outbursts: PCP stimulates the brain’s excitatory pathways, leading to impulsive, unpredictable reactions, including anger and violent behavior. This results in harm to oneself or others.
• Social withdrawal and isolation: The hallucinatory and paranoia-inducing effects of PCP make users distrustful of others, leading them to avoid social interactions and retreat from close relationships.

  Isolation is a key marker of addiction, as it reflects the individual’s increasing withdrawal from normal activities and support systems.

• Impulsive or risky actions: PCP impairs judgment and decision-making, causing users to engage in reckless behaviors such as driving under the influence, unsafe sex, or dangerous physical stunts. This reflects the drug’s disruption of the brain’s prefrontal cortex, responsible for planning and impulse control.
• Unpredictable and erratic behavior: The drug’s hallucinatory effects cause users to experience extreme mood swings, unpredictable actions, and disorganized thinking, which are alarming to others and worsen the person’s mental and emotional state.

Physical Signs

The physical signs of Phencyclidine (PCP) addiction include dilated pupils, numbness, and impaired motor skills.

A person under the influence of PCP displays noticeable changes in their physical condition. These include difficulty coordinating movements, walking unsteadily, or even experiencing numbness in the limbs.

Frequent users have dilated pupils, which serve as a visible sign of the drug’s impact on the nervous system. Over time, physical deterioration due to continued use also occurs, such as weight loss, poor hygiene, and neglect of personal care.

The physical signs of Phencyclidine (PCP) addiction are as follows:

• Dilated pupils: PCP is a stimulant that affects the autonomic nervous system, causing the pupils to expand. This is a visible sign of the drug’s influence on the body, signaling that the user has recently consumed the substance.
• Numbness or loss of sensation in the body: As a dissociative anesthetic, PCP causes users to experience a numbing effect on their body, which results in a reduced ability to feel pain or physical sensations.

  This is a sign of the drug’s anesthetic properties affecting the sensory nerves.

• Impaired motor skills and coordination: PCP affects the brain’s motor control centers, leading to difficulty with coordination, walking, and balance. This manifests as stumbling, unsteady movements, and the inability to perform basic motor tasks, which is a direct consequence of the drug’s action on the nervous system.
• Weight loss and poor hygiene: Chronic PCP use leads to neglect of self-care, including poor nutrition, irregular eating patterns, and lack of personal hygiene.

  Weight loss results from a combination of appetite suppression and neglect of daily living activities.

Psychological Signs

The psychological signs of Phencyclidine (PCP) addiction include paranoia, anxiety, and hallucinations. PCP profoundly affects the brain, leading to intense psychological symptoms.

Individuals experience delusions or distorted perceptions of reality, contributing to paranoia or excessive anxiety. These mental disturbances lead to difficulty distinguishing between what’s real and what’s influenced by the drug, which causes irrational fears, confusion, or disorganized thinking.

Hallucinations, both visual and auditory, are also common and further complicate the user’s mental state, potentially leading to dangerous situations.

The psychological signs of Phencyclidine (PCP) addiction are as follows:

• Paranoia and excessive fear: PCP distorts reality, leading users to believe they are being watched or persecuted. This paranoia is a direct result of the drug’s interference with brain function, specifically in areas responsible for managing anxiety and fear responses.
• Anxiety and agitation: PCP increases arousal in the nervous system, which leads to heightened anxiety, restlessness, and agitation.

  These symptoms are commonly seen during intoxication and withdrawal and reflect the overstimulation of the brain’s stress-response systems.

• Hallucinations (visual and auditory): One of the hallmark effects of PCP is its ability to cause vivid hallucinations. Users see or hear things that are not present, which are frightening or disorienting, leading to a distorted perception of reality.
• Delusions and disorganized thinking: PCP causes cognitive impairment, leading to confused thinking, irrational beliefs, and disorganized speech.

  These symptoms are indicative of the drug’s strong influence on the brain’s frontal cortex, which governs reasoning and logic.

What Causes PCP Addiction? 

The causes of Phencyclidine (PCP) addiction include a combination of biological, environmental, and psychological factors. PCP affects the brain’s neurotransmitter systems, particularly those involved in mood regulation, cognition, and sensory perception.

This alteration in brain chemistry is a key factor in the drug’s addictive potential.

The causes of Phencyclidine (PCP) addiction are as follows:

• Biological Factors: Genetics, brain chemistry, and individual physiology play an important role in addiction susceptibility. Some people are genetically predisposed to addiction due to variations in neurotransmitter function.

  According to a study published by Learn Genetics Utah, titled “Genes and Addiction,” a person’s genetics account for 40-60 percent of their risk. The way the brain responds to dopamine, serotonin, and other key chemicals increases the likelihood of developing a substance use disorder, including PCP addiction.

  Serotonin (5-HT) plays a significant role in addiction by affecting impulsivity and mood regulation. Abnormal serotonin levels can contribute to impulsive behaviors, which are associated with the development and maintenance of drug addiction, according to a study by Kirby LG, Zeeb FD, Winstanley CA. et al. 2011, titled “Contributions of serotonin in addiction vulnerability.” Substances like PCP can alter the brain’s neurons, which communicate through neurotransmitters, thus affecting an individual’s brain chemistry and increasing susceptibility to addiction, according to the Mayo Clinic in “Drug addiction (substance use disorder).”

• Environmental Factors: A person’s social environment greatly influences their risk of addiction.

  Growing up in a family or social circle where drug use is common or normalized increases exposure to PCP. Additionally, factors such as socioeconomic status, peer pressure, and stressors like trauma or neglect push individuals toward using drugs as a coping mechanism.

• Psychological Factors: Mental health conditions like anxiety, depression, or trauma overlap with substance use disorders. For example, someone with untreated mental health issues turns to PCP as a way to self-medicate, thus increasing the likelihood of developing an addiction.

  The drug’s ability to alter mood and provide temporary relief from psychological distress is particularly dangerous. An estimated 20% of those who have an anxiety disorder turn to addiction, according to the World Health Organization (WHO), as a coping mechanism.

What Are the Risk Factors for PCP Addiction?  

The risk factors for Phencyclidine (PCP) addiction include a combination of biological, environmental, and behavioral influences.

These factors combined significantly influence a person’s vulnerability to PCP addiction. The interplay of genetics, mental health, and environment makes it difficult to predict and prevent, but understanding these risk factors helps guide prevention and treatment efforts.

The risk factors for Phencyclidine (PCP) addiction are as follows:

• Age and Gender: Adolescents and young adults are at higher risk of developing addiction due to their ongoing brain development, which makes them more susceptible to the effects of drugs. Teenagers and young adults tend to be more vulnerable to addiction, as studied by Poudel A., Gautam S., et al. 2017, titled “Age of onset of substance use and psychosocial problems among individuals with substance use disorders.” For most age groups, men have higher rates of use or dependence on illicit drugs and alcohol than do women, according to a study by the Substance Abuse and Mental Health Services Administration (SAMHSA), Center for Behavioral Health Statistics and Quality in “Treatment Episode Data Set (TEDS): 2004-2014.”
• Genetics: A family history of addiction increases the risk, as genetic factors play a role in how individuals respond to substances.  According to a study published by Learn Genetics Utah, titled “Genes and Addiction,” a person’s genetics account for 40-60 percent of their risk.
• Mental Health Disorders: Individuals with underlying conditions such as depression, anxiety, or trauma are more likely to use drugs like PCP as a form of self-medication, raising the chances of developing an addiction.

  According to Healthline in “Unpacking the Complex Link Between Depression and Substance Use Disorders,” ”25% of people with Major Depressive Disorder (MDD) also have a substance use disorder.

• Environmental Factors: Exposure to environments where drug use is common, such as peer groups, family backgrounds, or neighborhoods with high levels of substance use, increases the risk. A secondary analysis of the 2013 National Survey on Drug Use and Health (NSDUH) titled “Socioeconomic Disparities and Self-reported Substance Abuse-related Problems” revealed that individuals from lower-income backgrounds were more likely to report substance abuse-related problems compared to those from higher-income households.

  Specifically, individuals in the lowest income group were 36% more likely to self-identify as having substance abuse issues. 

• Previous Substance Use: Those who have experimented with other drugs or alcohol are at a higher risk of trying PCP and potentially developing an addiction. A study of 1,130 clients seeking treatment for alcohol-related issues in Australia, conducted by Lawson S et al. 2024, titled “Prevalence and factors associated with polydrug use among clients seeking treatment for alcohol misuse,” found that 71% reported using at least one other drug, with tobacco (50%), cannabis (21%), and benzodiazepines (15%) being the most common.

  Excluding tobacco, 35% of participants engaged in polydrug use. 

What Are the Health Effects of PCP Addiction? 

The health effects of Phencyclidine (PCP) addiction include a wide range of short-term and long-term consequences that impact mental and physical well-being. These result in immediate dangers such as seizures, hallucinations, and psychosis, as well as longer-term risks like memory loss, (permanent) brain damage, and cardiovascular issues (heart attacks and heart palpitations).

The effects of PCP are severe and even life-threatening, affecting the brain, heart, and respiratory system. According to a study by Burns RS, Lerner SE. et al. 1978, titled “Phencyclidine deaths,” PCP overdose leads to death, primarily due to asphyxia from respiratory depression.

This effect is due to PCP’s behavioral toxicity and high concentrations, which impair breathing and lead to seizures.

Short-term Health Effects

The immediate effects of Phencyclidine (PCP) use include hallucinations, flashbacks, psychosis, and severe agitation. Individuals experience confusion, disorientation, and aggressive behavior. Dilated pupils and nystagmus (involuntary eye movements) are also common physical signs of PCP addiction.

PCP impairs motor skills, making users prone to accidents. Seizures and breathing problems, including asphyxia, occur in extreme cases, leading to serious medical emergencies.

Symptoms of PCP toxicity begin at doses as low as 0.05 mg/kg, with doses of 20 mg or more leading to severe outcomes such as seizures, coma, and even death. PCP is primarily metabolized in the liver, with about 10% excreted through the kidneys, as reported in a 2023 study by Journey JD and Bentley TP titled “Phencyclidine Toxicity.”

The short-term effects of Phencyclidine (PCP) addiction are as follows:

• Hallucinations: PCP disrupts the brain’s normal processing of sensory information, leading to vivid visual and auditory hallucinations. These are frightening and disorienting, contributing to a breakdown in perception of reality.
• Flashbacks: Flashbacks occur when the effects of PCP re-emerge suddenly after the drug’s active effects have worn off.

  This phenomenon is associated with lingering changes in brain function caused by the drug’s hallucinogenic properties.

• Nystagmus (involuntary eye movements): PCP affects the central nervous system, leading to involuntary eye movements, known as nystagmus. This symptom reflects the drug’s impact on the brain’s motor and visual processing centers.
• Dilated pupils: PCP acts as a stimulant on the nervous system, causing the pupils to dilate.

  This is a common physical sign of intoxication and is used to identify recent use.

• Aggression or violence: PCP alters mood regulation and decision-making, which leads to aggressive behavior and violent outbursts. This is a common behavioral consequence of the drug’s dissociative effects.
• Seizures: At higher doses, PCP induces seizures by overstimulating the brain.

  This is a severe short-term effect that requires immediate medical intervention to prevent long-term neurological damage.

• Breathing difficulties, asphyxia: PCP depresses respiratory function, causing difficulty breathing or even asphyxiation. This is a life-threatening short-term effect that occurs in extreme cases, especially when combined with other substances.

Long-term Health Consequences

Chronic Phencyclidine (PCP) addiction leads to (permanent) brain damage, with cognitive impairments such as memory loss and amnesia being common.

Phencyclidine induces a psychotomimetic state that closely resembles schizophrenia and psychosis, which is why, in animal experimental studies, PCP is used to investigate the neurochemical basis of schizophrenia.

Individuals experience cardiovascular problems, such as heart attacks or palpitations, as well as flushing skin that ends up in skin rashes. PCP long-term use causes erectile dysfunction and even sterility in men. In some cases, persistent use of PCP increases the risk of neutropenia, a condition that reduces white blood cell count and weakens the immune system. PCP-laced cigarettes, sometimes mixed with embalming fluid, cause significant health risks, including tissue damage and an increased risk of cancer.

The long-term effects of Phencyclidine (PCP) addiction are as follows:

• Permanent brain damage: Prolonged PCP use leads to irreversible changes in brain structure and function, particularly in areas involved in memory, decision-making, and emotional regulation. This brain damage results in long-lasting cognitive deficits and behavioral problems.
• Memory loss or amnesia: Chronic use of PCP impairs the hippocampus, the brain region responsible for memory formation.

  Users suffer from significant memory loss or amnesia, which affects both short- and long-term recollection.

• Heart attacks or palpitations: PCP increases heart rate and blood pressure, placing a strain on the cardiovascular system. Long-term use leads to heart palpitations and, in some cases, heart attacks due to the drug’s stimulatory effects on the heart.
• Erectile dysfunction and sterility: PCP affects hormone regulation, leading to sexual dysfunction in both men and women.

  In men, this manifests as erectile dysfunction or even infertility, as prolonged use disrupts normal reproductive health, as studied by Smith DE et al. 1980, titled “PCP and Sexual Dysfunction.”

• Health risks from PCP-laced cigarettes: PCP is sometimes combined with other substances, such as embalming fluid, and smoked in cigarettes. PCP-laced cigarettes, referred to as “wet” or “fry,” are a significant health hazard due to the toxic substances they contain.

  Smoking these cigarettes leads to severe lung injuries, including progressive hypoxemic respiratory failure, which impairs oxygen levels in the blood and damages lung function. This serious form of lung injury causes long-lasting respiratory issues, even after recovery.

  It also increases the risk of cancer due to the toxic substances in the mixture.

What Are Not the Effects of Phencyclidine (PCP) Addiction?

While Phencyclidine (PCP) abuse leads to a number of severe physical and mental health issues, some effects are commonly confused with PCP addiction but are not directly caused by it. For instance, although PCP use causes hallucinations and psychotic episodes, it does not cause schizophrenia.

Similarly, PCP is not linked to neutropenia or facial numbness, although it causes extremities numbness.

Does PCP Cause Violent Behavior or Aggressiveness? 

Yes, Phencyclidine (PCP) causes violent behavior and aggression in some users. Phencyclidine (PCP) disrupts normal brain function by altering neurotransmitter activity, particularly by blocking NMDA receptors, which play an integral role in cognition and emotional regulation. This disruption causes a sense of invulnerability and intense rage, contributing to unpredictable or aggressive behaviors, according to a study by Crane CA, Easton CJ, Devine S., et al. 2013, titled “The association between phencyclidine use and partner violence: an initial examination.”

What Are the Overdose Effects of PCP? 

The overdose effects of Phencyclidine (PCP) include seizures, coma, and even death. An overdose occurs if more than 20 milligrams of PCP is ingested at once, which leads to serious outcomes.

The overdose effects of Phencyclidine (PCP) are as follows:

• Seizures: Seizures are one of the first signs of PCP overdose, indicating severe neurological disruption.
• Coma: High doses of PCP depress the central nervous system to the point of inducing a coma.
• Death: Overdose on PCP ultimately results in death, particularly due to respiratory failure, seizures, or traumatic injury resulting from the user’s altered mental state.

In addition to these symptoms, other overdose effects include severe agitation, hallucinations, muscle stiffness, and high blood pressure, all of which put enormous strain on the body. 

What is PCP Withdrawal? 

Phencyclidine (PCP) withdrawal occurs as the body adapts to the absence of the drug, which results in a range of both physical and psychological symptoms. Since PCP (phencyclidine) significantly alters the brain’s chemistry, the withdrawal process includes a period of adjustment where users experience intense cravings, anxiety, and physical discomfort.

The PCP withdrawal process involves an initial phase where the user experiences agitation, confusion, and sometimes hallucinations. As time progresses, other symptoms, such as depression, fatigue, and disruptions in sleep patterns, emerge. This period of withdrawal is challenging and sometimes includes severe psychological effects as the brain rebalances after prolonged PCP use.

Managing PCP withdrawal requires medical support, given the intensity of symptoms and the risk of relapse. The withdrawal experience varies based on factors like the duration and intensity of use, making a structured detox program and supportive care essential for a safe and effective recovery.

What Are Common PCP Withdrawal Symptoms? 

The common Phencyclidine (PCP) withdrawal symptoms include a range of physical and psychological effects as the body and mind adjust to the absence of the drug. Withdrawal is particularly challenging due to the drug’s impact on the brain’s neurotransmitters and overall neurological functioning.

The common Phencyclidine (PCP) withdrawal symptoms are as follows:

• Intense cravings for the drug, as the brain has become accustomed to its effects.
• Anxiety and agitation accompanied by restlessness or irritability.
• Muscle pain and stiffness, as physical discomfort emerges.
• Depression and lethargy, with some individuals experiencing mood swings.
• Confusion and memory problems, as the brain begins to recalibrate without PCP.
• Headaches and other physical pains are part of the body’s response to withdrawal.

How long does PCP Withdrawal Last? 

Phencyclidine (PCP) withdrawal lasts for 7 to 14 days, with symptoms peaking in severity within the first few days after the last dose, according to Delamere titled “Drug Addiction Withdrawal & Symptoms.” The half-life of PCP is between 11 hours and 51 hours, depending on the amount you take and the method by which you take the drug. The initial phase, which includes intense cravings, anxiety, and irritability, occurs within the first 24 to 72 hours. This is followed by a period of up to two weeks where residual symptoms, like mood instability and sleep disturbances, persist. 

In some cases, psychological effects such as cravings and anxiety extend beyond this window, particularly for heavy or long-term users, though these usually lessen with time and support. The duration varies significantly among individuals, influenced by factors like dosage, frequency of use, and individual physiology. Withdrawal from 15 or 20 mg/kg/day PCP induced depression in brain reward function that lasted for the entire month of observation, according to a study by Spielewoy, C., Markou, A., et al. 2003, titled “Withdrawal from Chronic Phencyclidine Treatment Induces Long-Lasting Depression in Brain Reward Function.”

How Severe Is PCP Withdrawal? 

Phencyclidine (PCP) withdrawal varies from mild to severe. Physical symptoms of PCP withdrawal are mild and short-lived, but the psychological effects of PCP withdrawal are severe and last as long as 6 months to a year, according to a study by the National Center for Biotechnology Information et al. 2020 titled “Half-Life.” 

Physically, users experience symptoms like muscle pain, chills, nausea, and fatigue, which vary from mild to moderate depending on the individual’s history of use. Mentally, the symptoms are more distressing, with many experiencing strong cravings, anxiety, mood swings, and confusion, which may also lead to bouts of depression or agitation.

What Are Treatment Options for PCP Addiction?  

The treatment options for Phencyclidine (PCP) addiction include a combination of detoxification, therapy, medication-assisted treatment (MAT), and specialized rehabilitation programs. These approaches collectively address the physical, mental, and behavioral aspects of addiction, each providing necessary steps toward recovery.

The treatment options for Phencyclidine (PCP) addiction are as follows:

1. Detoxification

Detoxification is the initial process of clearing Phencyclidine (PCP) from the body, usually performed under medical supervision due to the potential for severe withdrawal symptoms. Medically supervised detox for PCP addiction is necessary, as it allows healthcare professionals to manage symptoms such as agitation, confusion, and potential aggression that are common with PCP withdrawal. 

Structured detox programs increase the likelihood of successful recovery, providing a safe environment for initial withdrawal management and preparing the individual for the next stages of treatment. According to data from SAMHSA, approximately 68% of individuals who complete detox programs for drug or alcohol dependency report their treatment as effective.

2. Therapy and Counseling

Therapy and counseling focus on treating the psychological aspects of Phencyclidine (PCP) addiction.

CBT application in addiction treatment is widely used, helping individuals recognize and change the thought patterns and behaviors associated with addiction. CBT is particularly effective in preventing relapse by equipping individuals with coping strategies to handle stress and cravings.

For PCP users, therapy targets behavioral regulation and helps manage impulsivity, both of which are crucial given the drug’s effects on mood and behavior.

Healthline notes that nearly 75% of people who begin cognitive behavioral therapy (CBT) experience positive results, while Very Well Mind reports that around 60% of individuals who use CBT for substance-related issues maintain recovery for a year. 

3. Medication-Assisted Treatment (MAT)

MAT uses medications to help manage withdrawal symptoms and reduce cravings, although no specific FDA-approved medications exist for Phencyclidine (PCP) addiction. However, Medication-assisted Treatment benefits in addiction treatment alleviate symptoms during recovery, such as antipsychotics for severe agitation or mood stabilizers to manage emotional irregularities.

The following medicines are known to treat PCP addiction:

• Antipsychotics: Medications like haloperidol help manage severe agitation and psychotic symptoms associated with PCP withdrawal.
• Mood stabilizers: Drugs like lithium or valproate are used to address mood swings and aggression in individuals recovering from PCP use.
• Benzodiazepines: Benzodiazepines are sometimes used to manage intense anxiety and agitation during withdrawal, though they must be used cautiously due to their own addictive potential.

4. Rehabilitation Programs

Rehabilitation programs provide structured environments for recovery, with options ranging from inpatient to outpatient care.

There are two main types of rehabilitation programs, inpatient and outpatient, which can further be classified as intensive outpatient rehab programs (IOP). According to Which Rehab in “Does Rehab Works,” the success rates of drug rehab treatments range from 30% to 70%, depending on the individual’s commitment to the treatment process and the effectiveness of the program.

The following rehabilitation programs help treat Phencyclidine (PCP) addiction:

• Inpatient Programs: Inpatient rehabilitation programs provide 24/7 medical care and support, ideal for individuals requiring a structured, drug-free environment. They require individuals to stay in the rehab facility for a certain period.

  According to NIDA, 50% of patients who remain in rehab for at least three months stay clean for at least two years. Longer treatment tends to produce the best outcomes.

• Outpatient Programs: Outpatient programs are designed for individuals who require significant treatment but still wish to stay at home and maintain some level of daily activity, such as work or school.

  It is ideal for patients with less intense symptoms. IOPs provide several hours of therapy each week, focusing on building coping strategies, life skills, and support systems.

  A study in the Journal of Substance Abuse Treatment found that Outpatient Programs achieve similar abstinence rates and reductions in substance use as residential treatment programs, with success rates between 50% and 70%.

• Dual Diagnosis Programs: Target individuals with co-occurring mental health disorders, addressing the complex interaction between mental health and addiction.

How to Prevent PCP Addiction? 

To prevent Phencyclidine (PCP) addiction, several strategies, including education, awareness, and support networks, are implemented, particularly targeting individuals at higher risk, such as teens or those in environments where substance use is more prevalent.

To prevent Phencyclidine (PCP) addiction, the following strategies are employed:

• Education and Awareness: Raising awareness about the risks of PCP, including its dangerous effects on both physical and mental health, helps deter use. Schools, community programs, and media campaigns serve to inform at-risk groups about the potential consequences.
• Support Networks: Strong family and community support systems play an important role in prevention.

  Providing a safe and encouraging environment reduces the likelihood of drug experimentation and abuse. Counseling, support groups, and access to mentors help individuals resist pressures to try drugs.

• Alternative Coping Strategies: Encouraging healthier coping mechanisms is vital for at-risk populations.

  Teaching adolescents and young adults to manage stress through physical activity, hobbies, or social engagement can provide alternatives to turning to substances like PCP.

How to Prevent Phencyclidine Addiction Relapse? 

To prevent phencyclidine (PCP) addiction relapse, a multi-faceted approach that addresses both the psychological and environmental factors contributing to addiction is important.

To prevent phencyclidine (PCP) addiction relapse, the following strategies are employed:

• Support Networks: It is important to build a strong network of family, friends, and fellow individuals in recovery. Support groups such as Narcotics Anonymous (NA) or specific recovery communities provide emotional support and accountability, helping individuals navigate triggers and avoid situations that may lead to relapse.
• Therapy and Counseling: Ongoing therapy, including cognitive behavioral therapy (CBT) and other forms of psychotherapy, helps individuals identify and manage the underlying triggers for substance use.

  Therapy also aids in strengthening coping mechanisms, which are necessary for long-term recovery.

• Lifestyle Changes: Making lifestyle changes that promote a healthy, drug-free life significantly reduces relapse risk. This includes engaging in physical activity, maintaining a balanced routine, and avoiding environments or social circles that encourage drug use.

  Mindfulness practices and stress management techniques are also effective in reducing the urge to relapse.

How to Help a Loved One Struggling with PCP Addiction? 

To help a loved one struggling with Phencyclidine (PCP) addiction, it’s important to recognize the signs early on. Behavioral changes, such as aggression or withdrawal from social activities, along with physical signs like dilated pupils or slurred speech, indicate a problem.

Offering emotional support in a non-judgmental way lets your loved one know they’re not alone. Encouraging them to seek treatment, especially in a structured setting like a residential rehab program, is an important step toward recovery.

Supporting them also means setting boundaries that prevent enabling the addiction and participating in the recovery process when possible. Programs like those offered at WhiteLight Behavioral Health in Columbus, Ohio, provide personalized addiction treatment and help individuals struggling with PCP addiction regain control of their lives.

Can PCP Addiction be Mistaken?  

Yes, Phencyclidine (PCP) addiction can sometimes be mistaken for other conditions due to overlapping symptoms and diagnostic challenges. Behavioral symptoms like aggression, hallucinations, and erratic behavior resemble those of different mental health disorders, making accurate diagnosis more complex. 

Some substances, such as dextromethorphan (found in cough medicine), cause a false positive for PCP in drug tests because dextromethorphan and PCP are both NMDA receptor antagonists, are dopamine agonists, and inhibit serotonin reuptake. This leads to confusion in treatment if the initial diagnosis is based solely on drug screening without further assessment or confirmation. Proper clinical evaluation is key to distinguishing true PCP addiction from other potential causes.

What Is Phencyclidine Abuse? 

Phencyclidine abuse is the use of phencyclidine (PCP) in ways that are harmful or outside of prescribed or intended medical contexts. Unlike PCP addiction, which is characterized by a compulsion to continue using the substance despite harmful effects, abuse involves using PCP occasionally or in high doses to experience its hallucinogenic or mind-altering effects. 

These effects lead to dangerous behaviors, impaired motor functions, and psychological distress. Abuse of PCP, especially by teens, is a public health concern.

Among teenagers and young adults, 225,000 individuals aged 12-17 and 777,000 aged 18 to 25 have experimented with phencyclidine (PCP). High school student usage rates, are particularly concerning, with over 3% of high school seniors reporting lifetime use and more than 1% using it in the past year, according to the University of Michigan’s Monitoring the Future Survey mentioned in a report by the National Drug Intelligence Center titled “PCP Fast Facts.”

How Is PCP Abused? 

PCP, or phencyclidine, is abused in various ways to enhance its psychoactive effects. Common methods include smoking by dipping cigarettes or marijuana joints into liquid PCP. This approach, known as “fry” or “wet,” is popular for its rapid onset. 

PCP is also snorted in powdered form or taken orally by swallowing tablets or capsules. In some cases, individuals dissolve powdered PCP and inject it directly, a method that increases the intensity of its effects but also raises the risk of severe health complications.

How Does Phencyclidine (PCP) Addiction Compare to Other Substances Addiction? 

Phencyclidine (PCP) addiction compares to other substance addictions in its potential for psychological dependency, behavioral toxicity, and physical risks. PCP’s intense dissociative effects, similar to ketamine, make it highly addictive due to its capacity to cause hallucinations and altered perceptions. However, PCP’s unique risk of severe aggression and violent behavior differentiates it from most other hallucinogens. 

Here’s a breakdown of how it compares to different substances in terms of addiction potential and effects:

• Ketamine: Like PCP, ketamine is a dissociative anesthetic, but it’s addiction potential is lower compared to PCP. Both drugs lead to tolerance and psychological dependence.
• LSD: LSD is a hallucinogen that is less likely to cause addiction or cravings, although it also alters perception, like PCP. LSD users do not exhibit the violent behaviors seen with PCP.
• MDMA: MDMA is known for its stimulating and empathogenic effects; MDMA is more likely to lead to psychological dependence than physical addiction without the aggression linked to PCP.
• Methamphetamine: Methamphetamine is a highly addictive substance that causes intense euphoria and leads to severe physical and mental health decline, with a different pattern of aggression and hyperactivity than PCP.
• Cocaine: Cocaine is primarily a stimulant, and cocaine addiction develops rapidly, with strong cravings and a high risk of overdose, but lacks the hallucinogenic effects of PCP.
• Heroin: Heroin is an opioid that is extremely addictive, with severe physical withdrawal, whereas PCP withdrawal is more psychological. Heroin’s effects differ as it lacks PCP’s hallucinogenic or violent tendencies.
• Psilocybin (Mushrooms): Psilocybin is not addictive and lacks the dissociative effects and aggression sometimes linked to PCP.
• DXM (Dextromethorphan): Dextromethorphan is an over-the-counter cough suppressant that causes dissociation in high doses.

  DXM is mildly addictive but less dangerous and less habit-forming than PCP.

• Salvia: Salvia is a powerful but short-lived hallucinogen. Salvia rarely leads to addiction, and its effects are brief compared to the prolonged high of PCP.
• Bath Salts (Synthetic Cathinones): Bath salts are highly addictive with severe psychological effects.

  Bath salts cause paranoia and aggression similar to PCP but are chemically different and more dangerous in overdose situations.